Acephate is readily absorbed by the skin of rats. Arch. This could be overcome by derivatization. Male mice were fed acephate five days a week for four weeks at doses up to 28 mg/kg/day, and then mated with untreated
from a single or limited exposure) in 50 percent of the treated
The half-life of acephate in the anaerobic clay sediment of a creek was between six and seven days. Dimethoate (Cygon, DeFend) 1981; Wang, et al. half-life will always depend on the amount of the
When occupational exposures occur or a worker complains of illness, tests are optimally performed within 24 hours. In insects, neonicotinoids cause paralysis which leads to death, often within a few hours. No physiological changes were observed at the highest doses
http://npic.orst.edu/factsheets/archive/acephatech.html. requirements, nor does it necessarily reflect the position of the Zinkl, J. G.; Roberts, R. B.; Shea, P. J.; Lasmanis, J. 10â20 spectra/s) and insufficiently sensitive, Highly compatible with existing spectral libraries, SIM decreases analytical scope (targeted analysis only) and requires inconvenient time-window set-ups, Increased sensitivity in selected ion monitoring (SIM) mode, Quantitation problems and space charge effects, Increased detection selectivity and confirmation ability using MS, Relatively slow scanning (max. dermal exposure. effect was 0.375 ppm. Wong, in Comprehensive Sampling and Sample Preparation, 2011. The intermediate, unstable complexes formed before the release of the âleavingâ groups (ZH and XOH) are not shown. Acephate affects daphnid reproduction, reducing the number of young. There was no history of acute poisoning. The LD50 for acephate in mallard ducks is 350 mg kgâ1; 140 mg kgâ1 in pheasants; >5000 ppm for the mallard and 1280 ppm for the bobwhite quail. Penetrant fungicides usually maintain control for much longer periods of time (14â21 days or longer) compared with contact/protectant fungicides and can move into new tissues during growth of the plant. Toxicological Characteristics of Organophosphate Poisoninga, ANNA B. LOWIT, in Toxicology of Organophosphate & Carbamate Compounds, 2006. decrease offspring survival and body weight in wild mammals. milligrams (mg) of chemical per kilogram (kg) of body
ACEPHATE 97UP is an insecticide for control of pests on selected agricultural crops and in certain non-crop areas. Acephate is a phosphoramide that is methamidophos in which one of the hydrogens is replaced by an acetyl group. lethal concentration (LC50) that causes death (resulting
which is another organophosphate insecticide registered by the U.S. EPA. Behera, B. C.; Bhunya, S. P. Studies on the genotoxicity of asataf (acephate), an organophosphate insecticide, in a
49, 1977, submitted to U.S. Forest Service by Douglas-fir
measure of acute toxicity is the lethal dose (LD50) or
When acephate is eaten, it is quickly absorbed from the gastrointestinal tract in rats and humans. One study measured urine levels of acephate and methamidophos in humans exposed to acephate while farming in fields. hours. J. Spassova, D.; White, T.; Singh, A. K. Acute effects of acephate and methamidophos on acetylcholinesterase activity,
From: Encyclopedia of Toxicology (Third Edition), 2014, S. Karanth, in Encyclopedia of Toxicology (Third Edition), 2014. synthesis in and release from the hypothalamus in vitro. Symptoms from organophosphates can become apparent within minutes to hours after exposure,
A product containing acephate was applied to three sites in a stream in British Columbia, Canada for five hours at levels
Acephate and Buprofezin Residues in Olives and Olive oil / Caboni P; Cabras P. - (2010). The mice were administered oral doses of 0.28â8.96 mg/kg body weight of chlorpyrifos and 12.25â392.00 mg/kg body weight of acephate. acephate is present and the length and frequency of exposure. J. Marshall Clark, Michael P. Kenna, in Hayes' Handbook of Pesticide Toxicology (Third Edition), 2010. Medvedovici, in Encyclopedia of Analytical Science (Second Edition), 2005. Acephate is a general-use insecticide registered for use on food crops, agricultural
The relationship between tumor occurrence and acephate dose was not linear. In another study, rats were given 178 mg/kg acephate by gavage daily for four, fourteen, or sixty days. Sometimes, the inherent selectivity of LC affords separation of the tautomeric structures, leading to serious peak splitting, mainly at low concentration of the target compounds. with a scientific background and/or familiarity with toxicology and risk assessment. In order to extract both nonpolar pesticides â organochlorines â and polar pesticides â organophosphorus pesticides such as methamidophos and acephate, Luke et al.16 developed an extraction procedure, which involves acetone extraction followed by multiple steps of partitioning, salting out (petroleum etherâdichloromethane and dichloromethaneâNaCl), solvent exchange, and concentration. Pesticides may induce oxidative stress by excess generation of free radicals, especially reactive oxygen species and reactive nitrogen species, and alteration in antioxidants and the scavenging system, causing lipid peroxidation (Banerjee et al., 1999; Dettbarn et al., 2001; Gupta et al., 2001a,b, 2002; Etemadi-Aleagha et al., 2002). Acephate can kill target insects when they touch it or eat it. These efforts have led to substantial reduction in exposures to these chemicals in food and in or around the home. After
The N-methyl CM cumulative risk assessment will likely be more refined and sophisticated. days in half-saturated silt clay loam soil. SAMOS, OSP2A). OPIDN effects may include leg muscle pain, followed by numbness, weakness or paresthesia beginning in the
Base rotations for resistance management on the mode of action number only. Acephate is an organophosphate foliar and soil insecticide of moderate persistence with residual systemic activity of about 10â15 days at the recommended use rate. of a person and/or certain environmental factors. In male rats that were fed the same doses, no significant increases in tumor incidence was noticed. See the pesticide label on the product and refer to
Acephate exerts its toxicity by inhibiting the enzyme acetylcholinesterase in the synapse and neuromuscular junctions, which leads to accumulation of the neurotransmitter acetylcholine and overstimulation of postsynaptic receptors. Their characteristic sensitivities can be considered to vary in the following order: ELSD