So if you have a severe milk protein allergy, you may have an allergic reaction to this medication. It should be stored in a dry place and kept away from sunlight and heat. However, beta-blockers can block the effects of Trelegy Ellipta and cause the medication to not work properly. Brand-name medications usually cost more than generics. If you have questions about how to treat sudden breathing problems while taking Trelegy Ellipta, talk with your doctor. Instead, you’ll use a rescue inhaler for sudden trouble breathing. MNT is the registered trade mark of Healthline Media. Could prostate drugs reduce Parkinson's disease risk? The inhaler isn’t reusable, and you can’t refill it. They may suggest a medication other than a beta-blocker. There have been reports of serious allergic reactions, including anaphylaxis, when people with milk allergies take Trelegy Ellipta. Because Trelegy Ellipta can also affect your heart rhythm, you shouldn’t take these medications while using Trelegy Ellipta. Clinical trials have shown that when a LABA is used in combination with an ICS, using the LABA does not increase the risk of asthma-related death and hospitalization. It’s not known if Trelegy Ellipta is safe to take during pregnancy. Note: Neither Trelegy Ellipta nor Symbicort is approved to treat sudden trouble breathing. Acute narrow-angle glaucoma can cause permanent loss of vision if not treated. It depends on what types of eye problems you have. If you pop an antihistamine every day to … Below is a list of medications that can interact with Trelegy Ellipta. It contains these three active drugs that help relieve breathing symptoms of COPD and asthma: Trelegy Ellipta comes as an inhaler. I’ve just changed from Symbicort to Fostair as I felt the Symbicort wasn’t helping as much as it used to. If you have sudden breathing problems, your doctor will likely want you to use a rescue inhaler. For more information about Trelegy Ellipta’s approved uses, see the “Trelegy Ellipta for COPD” and “Trelegy Ellipta for asthma” sections below. (For more about possible side effects of Trelegy Ellipta, see the “Trelegy Ellipta side effects” section above.) The drug should not be used to treat acute bronchospasm associated with either COPD or asthma. You should store your Trelegy Ellipta inhaler at room temperature between 68°F and 77°F (20°C and 25°C). A medication timer may be useful, too. If you’re taking a high dose or have used inhaled steroids for a long time, you may experience weight gain due to an increase in appetite. Certain antidepressant medications can interact with Trelegy Ellipta. If you open and close the cover of the inhaler without inhaling the medication, you’ll lose the dose. They can discuss rescue inhaler options with you. Keep Trelegy Ellipta in a dry place, away from sunlight and heat. Trelegy Ellipta may not be right for you if you have certain medical conditions or other factors affecting your health. GlaxoSmithKline LLC, the manufacturer of Trelegy Ellipta, offers a coupon for the medication. As a single oral inhaler, fluticasone is known as. Type 2 diabetes and high blood sugar lower glutathione in the body. And too much cortisol can lead to weight gain. Taking these steps can go a long way toward countering any potential weight gain these meds can cause. Its metabolites have minimal activity. Here are some examples of other drugs that may be used to treat chronic obstructive pulmonary disease (COPD). According to estimates on GoodRx.com, Trelegy Ellipta costs significantly more than Symbicort. Weight … These allergic reactions can be serious. These drugs haven’t been directly compared in clinical studies. The use of Trelegy Ellipta and Breo Ellipta in treating COPD has been directly compared in a clinical study called the IMPACT trial. These lists don’t include all possible side effects. After an intravenous dose, 58% is excreted in the feces and 22% is excreted in the urine. There are currently no generic forms of either drug. They may be able to suggest a different treatment. Although not all of these side effects may occur, if they do occur they may need medical attention. For asthma, the recommended dosage of Trelegy is one inhalation (puff) of Trelegy Ellipta once a day. This list contains examples of serious side effects that can occur with Trelegy Ellipta, with Breo Ellipta, or with both drugs (when taken individually): Trelegy Ellipta and Breo Ellipta are both approved to treat COPD and asthma in adults. Trelegy Ellipta is a brand-name prescription medication. * This serious side effect is explained in more detail below in “Side effect details.”. In clinical studies, back pain occurred in 2% to 4%* of people who took Trelegy Ellipta. However, no allergic reactions were reported as a side effect of the drug in clinical trials. Trelegy Ellipta and Symbicort both contain medications that work in similar ways to treat your COPD. Never stop taking prescribed medication unless your GP or specialist has told you to. Bronchitis If experienced, these tend to have a Less Severe expression 1. For information about this, see the “Trelegy Ellipta use with other drugs” section below. Trelegy Ellipta is a combination medication that’s used to treat asthma. Inhaled corticosteroids, also known as steroids or glucocorticoids, can cause side effects like insomnia or thrush, and strategies like rinsing your mouth after you use them might help reduce some side effects. Trelegy Ellipta is an inhaled medication that’s used for long-term treatment of chronic obstructive pulmonary disease (COPD) and asthma. * This is a partial list of mild side effects from Trelegy Ellipta. Fluticasone is an inhaled steroid medication. Trelegy Ellipta should be stored at room temperature between 68°F and 77°F (20°C and 25°C). However, it’s possible for the long-term use of inhaled steroids to cause weight gain. Weight gain isn’t a side effect that’s been reported with Trelegy Ellipta use. For information about this, see the “Trelegy Ellipta use with other drugs” section below. They may suggest other medications. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. So in theory, it’s possible for Trelegy Ellipta to cause … If you’re having sudden trouble breathing, your doctor will likely want you to use a rescue inhaler such as albuterol (Ventolin HFA, ProAir) or levalbuterol (Xopenex). If you and your doctor determine that Trelegy Ellipta is safe and effective for you, you’ll likely take it long term. This is because it can take time for the medications in Trelegy Ellipta to begin working. Doxylamine succinate often causes drowsiness, which is considered a beneficial effect when used as a sleep aid but a side effect when used for other purposes 4⭐⭐This is a verified and trusted source Goto Source . Rinse your mouth with water without swallowing after using TRELEGY to help reduce your chance of getting thrush. In animal studies, umeclidinium was seen in the breast milk of mothers who were given the drug. You should take Trelegy Ellipta according to your doctor’s or healthcare provider’s instructions. It should be stored in the unopened foil tray until it is ready for use. However, the three drugs (fluticasone, umeclidinium, and vilanterol) in Trelegy Ellipta have been studied separately. You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. There may be another medication to treat your infection that won’t interact with Trelegy Ellipta. This is compared with 3% to 7%* of people who took only fluticasone and vilanterol (two of the three ingredients in Trelegy Ellipta). The following lists contain some of the key side effects that may occur while taking Trelegy Ellipta. The medication is in a powder form, and you’ll inhale it into your lungs as you take one deep breath. You should avoid using these medications for at least 2 weeks before you start Trelegy Ellipta treatment. (For more about anticholinergics, see “Trelegy Ellipta and other anticholinergic medications” right below.). In another clinical study, Trelegy Ellipta was compared with the two active ingredients in Breo Ellipta. If you have sudden trouble breathing, your doctor will likely want you to use a rescue inhaler such as albuterol (Ventolin HFA, ProAir) or levalbuterol (Xopenex). In these animal studies, there were no harmful effects on babies whose mothers were given fluticasone or umeclidinium while pregnant. Trelegy Ellipta contains fluticasone, which is an inhaled steroid. The manufacturer conducted 12-week, 24-week and one-year long safety studies to evaluate side effects associated with Trelegy. Instead, you’ll use a rescue inhaler for sudden trouble breathing. If you’re breastfeeding, talk with your doctor before taking Trelegy Ellipta. There have been reports of severe allergic reactions occurring in people with milk protein allergies who took other powder medications with lactose in them. Trelegy Ellipta is approved for long-term treatment of chronic obstructive pulmonary disease (COPD) and asthma. Note: Some of the drugs listed here are used off-label to treat these specific conditions. And this can cause the level of Trelegy Ellipta in your body to be too high, increasing your risk for side effects. The drug isn’t meant to be used for sudden breathing problems caused by COPD. How long does it take for Trelegy to work? To find current prices for Trelegy Ellipta in your area, check out GoodRx.com. You can use your rescue inhaler in between your doses of Trelegy Ellipta if you have flare-ups of COPD or asthma symptoms. Steroids cause weight gain by altering the body’s electrolyte and water balances, as well as its metabolism — the way it uses and stores lipids, amino acids, protein, … Trelegy Ellipta is contraindicated for use in people with severe milk protein allergies. A long-term study of Trelegy Ellipta looked at side effects of the medication over the course of 52 weeks. In this trial, forced expiratory volume in 1 second (FEV1) was measured. You’ll take one inhalation (puff) of the medication once a day. This may help decrease your risk of getting oral thrush, which is a fungal infection in your mouth. Higher FEV1s show better lung function, while lower FEV1s show poorer lung function. If you would like to report to the FDA a side effect you’ve had with Trelegy Ellipta, you can do so through MedWatch. Select one or more newsletters to continue. Thrush is a fungal infection that can occur due to the use of inhaled steroids such as fluticasone, one of the drugs in Trelegy Ellipta. If you develop back pain from taking Trelegy Ellipta, talk with your doctor. Does Flomax Cause Water Retention This water retention can appear to be weight gain. There’s no human data available to determine if any or all of the ingredients in the medication are safe for use while pregnant. It is primarily metabolized via CYP3A4 and is also a substrate of P-glycoprotein transporter. However, you may not notice a change in your breathing symptoms right away. Trelegy Ellipta is a long-term treatment that will work over time to ease COPD and asthma symptoms and help you breathe easier. Consuming other medicines with sedating effects -- such as antidepressants, muscle relaxants or opioid painkillers -- and dri… Instead, you’ll use a rescue inhaler for sudden trouble breathing. You may wonder how Trelegy Ellipta compares with other medications that are prescribed for similar uses. You may be able to. Other combination medications that may be used to treat COPD include: Other medications that may be used to treat COPD include: Note: Trelegy Ellipta and the alternative drugs listed here are meant to be used over time to control COPD symptoms. Both Trelegy Ellipta and Breo Ellipta are dry powder inhalers. In general, use of inhaled corticosteroids (“steroids”) over the long-term has rarely been associated with weight gain. Serious side effects from Trelegy Ellipta aren’t common, but they can occur. Lactose is an inactive ingredient in Trelegy Ellipta that helps the medication reach your lungs. However, other people don’t feel or taste the medication, even if they use the inhaler properly. Below are examples of these side effects. In clinical trials, 4% to 9%* of people who took Trelegy Ellipta developed headaches. They can recommend ways to help ease the pain. Rinse your mouth with water without swallowing after using TRELEGY to help reduce your chance of getting thrush. If you’re sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while you’re using Trelegy Ellipta. For information about this, see the “Trelegy Ellipta use with other drugs” section below. However, this doesn’t mean that Trelegy Ellipta will be present in human breast milk. In clinical trials, Trelegy Ellipta was effective in treating COPD. And some of these side effects can become serious, such as overheating or hallucinating. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. With emphysema, your lungs are damaged and have trouble passing air in and out. In comparison, back pain only occurred in about 1% to 4%* of people who took only fluticasone and vilanterol (two of the three ingredients in Trelegy Ellipta). Three active drug ingredients make up Trelegy Ellipta: fluticasone furoate, umeclidinium, and vilanterol. Once opened, the tray is good for only 6 weeks. Has anyone on Fostair noticed weight gain? † This mild side effect is explained in more detail below in “Side effect details.”. If you're concerned about weight gain… For more information about this, see the “Trelegy Ellipta use with other drugs” section below. What can I do? Cmax was reached about 30 minutes to 1 hour post-dose. An inactive ingredient is any part of the medication that’s not the active ingredient.). Umeclidinium is minimally orally absorbed. Store the inhaler in the unopened tray until you’re ready to use it. Your doctor or pharmacist may also be able to recommend ways to help prevent a thrush infection from occurring in the future. This may cause the anti-inflammatory effects that are seen with fluticasone treatment. weight gain Rare. This is because both of these medications have a drug called an anticholinergic in them. Trelegy Ellipta contains three active drug ingredients: fluticasone furoate, umeclidinium, and vilanterol. However, in rats it is believed that pro-inflammatory transcription factors are inhibited along with antigen-induced lung eosinophilia. It’s available only as a brand-name medication. Unexpected weight gain can be a mentally frustrating. They aren’t meant to be used for sudden breathing problems caused by asthma. However, because there are three different drugs in Trelegy Ellipta, taking too much Trelegy Ellipta would mean taking too much of all three drugs. And you’ll usually keep coughing up mucus. Some patients may be fearful of exercising due to the risk of triggering COPD or asthma symptoms. Trelegy Ellipta is meant to be used as a long-term treatment. Its half-life is 11 hours. Research Triangle Park, NC: GlaxoSmithKline. After oral administration, 70% of the drug was recovered in urine and 30% was recovered in feces. Instead, you’ll use a rescue inhaler for sudden trouble breathing. Review the full Trelegy Ellipta information here, and discuss this information with your doctor or other health care provider. Can you take Trelegy and Symbicort together? Call 911 if your symptoms feel life threatening or if you think you’re having a medical emergency. Drowsiness tends to be more common and more severe in older adults. So it’s important that you keep taking Trelegy Ellipta every day even if you don’t notice a difference in your breathing right away. But in Trelegy, it’s combined with fluticasone, an inhaled corticosteroid (ICS), and umeclidinium, an anticholinergic. This medication works mainly in your lungs and isn’t absorbed well into your body. Each inhaler has two foil strips inside it that contain blisters of the medication. There are a total of 30 doses in each Trelegy Ellipta inhaler. Symptoms of thrush include mouth pain or white patches in the mouth. There were no overdoses reported in people who took Trelegy Ellipta in clinical studies. Examples of non-potassium sparing diuretics include: If you’re taking a non-potassium sparing diuretic, tell your doctor before you start using Trelegy Ellipta. For more information, see the “Trelegy Ellipta for asthma” section below. Antimicrobial drugs are medications that are used to treat infections. Trelegy Ellipta is a combination medication that’s used to treat symptoms of chronic obstructive pulmonary disease (COPD). Antihistamines. Available for Android and iOS devices. pneumonia. Note: Trelegy Ellipta is meant to be used over time to control COPD symptoms. ... unusual weight gain … seen the dr, dietry nurse even a dietition none of which can help. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Joint Pain 7. TRELEGY … For people with COPD, bloating and difficulty breathing can occur in a … So in theory, it’s possible for Trelegy Ellipta to cause you to gain weight. These metabolites are either minimally active or have not yet been studied to determine activity. The following information describes dosages that are commonly used or recommended. Give meatless Mondays a try. TRELEGY can cause serious side effects, including: fungal infection in your mouth or throat (thrush). Avoid storing this medication in areas where it could get damp or wet, such as in bathrooms, as it is a dry powder inhaler. It’s FDA-approved for the long-term maintenance treatment of: However, Trelegy Ellipta isn’t approved for use as a rescue inhaler to ease sudden breathing problems caused by either COPD or asthma. These include: Note: For more information about the potential negative effects of Trelegy Ellipta, see the “Trelegy Ellipta side effects” section above. Off-label use is when a drug that’s approved to treat one condition is used to treat a different condition. If you miss a dose of Trelegy Ellipta, take it as soon as you remember. If you have a milk allergy, talk with your doctor about safe treatments for your condition. There’s also a video on the manufacturer’s website that shows you the correct way to take Trelegy Ellipta. Note: Trelegy Ellipta is meant to be used over time to control asthma symptoms. thrush fungal infections (oral candidiasis), fluticasone, a corticosteroid, lowers inflammation (swelling) in the lung airways, vilanterol, a long-acting beta-agonist (LABA), relaxes the airway muscles. For more information about COPD and asthma, see the “Trelegy Ellipta for COPD” and “Trelegy Ellipta for asthma” sections above. They can recommend medication to treat the current infection. Selected from data included with permission and copyrighted by First Databank, Inc. ... TRELEGY may increase the chance of getting pneumonia Ginkgo biloba side effects blood pressure drastically, which may cause … However, it’s possible that alcohol may worsen chronic obstructive pulmonary disease (COPD) or asthma symptoms, which Trelegy Ellipta is used to treat. Weight gain has not been reported as a side effect with Trelegy Ellipta when used to treat asthma or chronic obstructive pulmonary disease (COPD). A certain type of diuretic called a non-potassium sparing diuretic can cause a decrease in your potassium level. Using more than the recommended dosage of Trelegy Ellipta can lead to serious side effects. Mild side effects* of Trelegy Ellipta can include: Most of these side effects may go away within a few days or a couple of weeks. If you have concerns about gaining weight while taking Trelegy Ellipta, talk with your doctor. Consumer Medicine Information (CMI) about Trelegy Ellipta (Fluticasone furoate 100 micrograms, umeclidinium 62.5 micrograms and vilanterol 25 micrograms per inhalation) … “Trelegy” is the brand name of the medication inside the inhaler. Beta-blockers are common medications that help decrease blood pressure and steady your heart rhythm. If experienced, these tend to have a Severe expression 1. In 2017, the Food and Drug Administration (FDA) approved Trelegy Ellipta to treat COPD. Fluticasone / umeclidinium / vilanterol, For example, Trelegy Ellipta contains fluticasone, an inhaled corticosteroid. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. In addition to being FDA-approved to treat chronic obstructive pulmonary disease (COPD), Trelegy Ellipta is also FDA-approved to treat asthma. This is an inhaler that dispenses the drug as a spray, which you breathe into your lungs. There were no reports of weight gain in this study. Like Breo Ellipta (above), the drug Symbicort has uses similar to those of Trelegy Ellipta. Some people do feel or taste Trelegy Ellipta after taking it. COPD is a group of lung conditions that include chronic bronchitis and emphysema, and it can cause wheezing, coughing, and trouble breathing. To help make sure that you don’t miss a dose, try setting a reminder on your phone. Here are some examples of other drugs that may be used to treat asthma. If you don’t use all 30 doses in 6 weeks, the inhaler is expired and you should throw it away. However, as mentioned above, weight gain wasn’t a side effect of Trelegy Ellipta reported in clinical trials. They may be able to recommend a different medication that doesn’t interact with Trelegy Ellipta. As with most drugs, some people can have an allergic reaction after taking Trelegy Ellipta. Symbicort has two active drug ingredients in it: budesonide and formoterol. The insurance company will review the information and let you and your doctor know if your plan will cover Trelegy Ellipta. It is mainly eliminated via the fecal route after an intravenous dose is given. The word “Ellipta” refers to the specific type of inhaler that contains the drug. This can cause an infection in your lungs and make it hard for you to breathe. Don’t take more than one dose in 24 hours. TRELEGY … For information about this, see the “Trelegy Ellipta use with other drugs” section below. For instance: In addition to being FDA-approved to treat asthma, Trelegy Ellipta is also FDA-approved to treat chronic obstructive pulmonary disease (COPD). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Higher FEV1s show better lung function, while lower FEV1s show poorer lung function. For chronic obstructive pulmonary disease (COPD), the recommended dosage of Trelegy is one inhalation (puff) of Trelegy Ellipta 100/62.5/25 mcg once each day. This can cause wheezing and fatigue (lack of energy). People with chronic obstructive pulmonary disease (COPD) can improve their symptoms using various home remedies. Because Trelegy Ellipta can also decrease your potassium level, the combination of these medications can be dangerous. The studies showed that FEV1 in people who took Trelegy Ellipta was between 122 mL and 124 mL higher than it was in people who took fluticasone and vilanterol. The most common side effects with Trelegy include: These are not all of the side effects that can occur with Trelegy Ellipta. Trelegy Ellipta is approved for use in adults ages 18 years and older. They can give you tips on how to deal with any side effects that may be bothersome. Trelegy Ellipta and Breo Ellipta are both brand-name drugs. Instead, you’ll use a rescue inhaler for sudden trouble breathing. Fluticasone furoate has a very low oral systemic bioavailability, about 1.3%. If you’re interested in finding an alternative to Trelegy Ellipta, talk with your doctor. In the trials, Trelegy Ellipta was compared with two of its three drugs: fluticasone and vilanterol. Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. And too much cortisol can lead to weight gain. Some of the most common side effects reported for Trelegy Ellipta when used for asthma or COPD include upper respiratory tract infection, bronchitis, sinusitis, sore throat, headache, back pain, and urinary tract infections, among others. Breo Ellipta contains two active drug ingredients: fluticasone and vilanterol. For information about the effectiveness of Trelegy Ellipta, see the “Trelegy Ellipta for COPD” and “Trelegy Ellipta for asthma” sections below. It’s not currently available in generic form. If the drug does cause side effects, you may have: A vilanterol overdose may include serious symptoms, such as: Because these medications can affect the heart, your doctor will monitor your heart if you take too much Trelegy Ellipta. Other drugs that may prolong your QT interval include: If you take any of these medications or other drugs for your heart rhythm, talk with your doctor before you start Trelegy Ellipta treatment. However, you should still check with your doctor or pharmacist before using any of these products while taking Trelegy Ellipta. For more information, see the “Trelegy Ellipta for COPD” section above. The following information is provided for clinicians and other healthcare professionals. Call your doctor right away if you have serious side effects. Throat Irritation 9. Inflammation Of The Tissue Lining The Sinuses 6. You shouldn’t take Trelegy Ellipta if you’re also taking tiotropium (Spiriva). Trelegy Ellipta contains lactose as a major excipient. Weight gain has not been reported as a side effect with Trelegy Ellipta when used to treat asthma or chronic obstructive pulmonary disease (COPD). Symptoms of acute narrow-angle glaucoma may include: eye pain or discomfort nausea or vomiting blurred … Sharing this information can help you avoid potential interactions. Together, these drugs work in the body to decrease inflammation and increase the space in the airways to allow more air into the lungs. The drugs work in the following ways to help relieve your COPD symptoms: Trelegy Ellipta should start working after your first dose. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Vilanterol is also minimally absorbed orally. You can prevent thrush from developing by always rinsing your mouth after you take your dose of Trelegy Ellipta. The oral corticosteroid medications that are often needed to treat severe eosinophilic asthma or EGPA are well known to cause weight gain. What is the best time of day to take Trelegy? Last updated on Sep 15, 2020. Some people with small-cell lung cancer cell get Cushing's syndrome. Trelegy Ellipta may cause headaches. The medication is in a powder form that you breathe into your lungs. If you have sudden trouble breathing, your doctor will likely want you to use a rescue inhaler such as albuterol (Ventolin HFA, ProAir) or levalbuterol (Xopenex). Its Cmax occurs about 5 to 15 minutes post-dose. These lists contain examples of mild side effects that can occur with Trelegy Ellipta, with Symbicort, or with both drugs (when taken individually). Below are examples of these side effects. Its Cmax occurs at 5 to 15 minutes post-dose. In the trials, Trelegy Ellipta was compared with a combination of placebo plus two of its three drugs: fluticasone and vilanterol. Here’s some information about the forms of each drug and how you take them. Don’t use this medication more than once in 24 hours. i have the opposit problem. vilanterol, which is a long-acting beta2-agonist (LABA), a bone that breaks more easily than it should, seeing halos or bright colors when looking at lights, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, one strip holds either 100 micrograms (mcg)* or 200 mcg** of fluticasone in each blister, the other strip holds 62.5 mcg of umeclidinium and 25 mcg of vilanterol in each blister, people who took Trelegy Ellipta had 15% fewer flare-ups each year than people who took fluticasone and vilanterol (two of the three drugs in Trelegy Ellipta), people who took Trelegy Ellipta had 25% fewer flare-ups each year than people who took umeclidinium and vilanterol (two of the three drugs in Trelegy Ellipta), 16% of people who took fluticasone and vilanterol, a long-acting beta2-agonist (LABA) and an, asthma symptoms aren’t well controlled on a long-term asthma medication such as an inhaled corticosteroid ICS), or, asthma is severe enough that it needs to be treated with both an ICS and a long-acting beta2-agonist (LABA) drug. 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Decreasing inflammation, which is an inhaled corticosteroid ( ICS ), the cost of Trelegy Ellipta, contact insurance... Needed to treat one condition is used to treat one condition is used for does trelegy cause weight gain use of Ellipta! 12:11 pm lead to weight gain according to estimates on GoodRx.com is what you may wonder how Trelegy....